Nucleofill
Nucleofill is one of the most popular treatments in medical aesthetics today. Derived from salmon DNA, it is administered through mesotherapy, allowing it to reach the deeper layers of the skin. By nourishing and repairing the tissue from within, Nucleofill restores hydration and supports skin regeneration, resulting in a more youthful, radiant appearance. But what exactly is Nucleofill, and how does it differ from Nucleofill Eyes?
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What is Nucleofill?
Nucleofill is a biostimulating treatment made from polynucleotides derived from salmon DNA. It works by stimulating cell regeneration at the deepest layers of the skin and gradually moves to the surface, improving tissue quality and skin elasticity. The result is visibly firmer, more hydrated, and glowing skin.
This non-invasive procedure is performed using mesotherapy, ensuring no incisions or scars. By replenishing moisture and enhancing skin health at the cellular level, Nucleofill is a highly effective anti-aging solution. However, it is essential to consult a medical specialist to determine suitability before undergoing treatment.
What is Nucleofill Eyes?
As the name suggests, Nucleofill Eyes is a specialized version of Nucleofill designed specifically for the delicate under-eye area. It effectively targets signs of aging such as fine lines, wrinkles, dark circles, puffiness, and tired-looking eyes. Due to repetitive facial expressions and thin skin in this area, signs of fatigue and aging often appear earlier here.
Nucleofill Eyes rejuvenates the under-eye area by improving microcirculation, stimulating collagen production, and deeply hydrating the skin. The result is a brighter, smoother, and more refreshed appearance. Since it is a non-surgical and scar-free treatment, it delivers natural yet noticeable results.

What Does Nucleofill Do?
Nucleofill offers a wide range of benefits that contribute to a naturally youthful appearance:

How is Nucleofill Done?
Before the procedure, a consultation is carried out to assess the patient’s skin condition and expectations. Since each person’s skin is unique, the treatment plan is tailored accordingly.
A topical anesthetic may be applied to minimize discomfort. The product is then injected into targeted areas using the mesotherapy technique. Depending on the individual’s skin structure and age, treatment may require one to three sessions.
After each session, the skin’s repair and regeneration process begins. Once the treatment cycle is complete, patients typically notice a visibly rejuvenated and radiant complexion with long-lasting effects.
Who is Suitable for Nucleofill?
Nucleofill is suitable for a wide range of individuals who are seeking non-surgical skin rejuvenation. It is especially beneficial for those experiencing early signs of aging or skin dehydration. However, it is essential to undergo a medical evaluation to rule out contraindications.
The treatment is not recommended for pregnant or breastfeeding women.


Are There Side Effects of Nucleofill DNA Sparkle?
Nucleofill DNA Sparkle is formulated with natural, biocompatible ingredients, significantly reducing the risk of side effects. Minor reactions such as redness or mild swelling may occur but usually resolve within a short time.
To ensure safety, a comprehensive consultation and skin analysis are performed before the procedure. As with any aesthetic treatment, results and reactions may vary by individual, but most patients return to their normal routines immediately after the session.
Nucleofill DNA Sparkle Benefits
Nucleofill DNA Sparkle provides multiple benefits for skin health and appearance:
- Equalizes skin color.
- Creates bio stimulating effect.
- Renews the skin.
- Corrects fine wrinkles.
- Eliminates free radicals.
- It increases the elasticity of the skin.
- Recovers sagging of the skin.
- Stimulates the tissues under the skin.
- Prevents and restores moisture loss of the skin.
- Provides a youthful appearance to the skin.
- Provides skin resistance and prevents possible losses.
Nucleofill DNA Glow
Nucleofill DNA Glow is gaining popularity due to its ability to deliver natural, glowing skin. The results may vary depending on factors such as skin type, age, and the area treated. However, most individuals experience visible improvements after treatment.
This technique stands out for its safety, minimal downtime, and long-lasting effects. Thanks to its natural formulation, it is well-tolerated by most patients, with minimal risk of complications.


Nucleofill Eyes Before and After
Aging signs around the eyes can affect self-confidence, and many people seek solutions to regain a refreshed appearance. Nucleofill Eyes offers a visible transformation by minimizing wrinkles, firming sagging skin, and improving hydration levels.
Before-and-after comparisons clearly show smoother, brighter skin with reduced signs of fatigue. This transformation not only enhances aesthetic appeal but also boosts self-esteem and confidence.
Nucleofill Costs
The cost of Nucleofill treatment can vary depending on several factors:
- The area being treated
- Number of sessions required
- The amount of product used
- Clinic location and reputation
- The experience of the doctor performing the procedure
While it may be tempting to opt for lower-cost treatments, it’s important to ensure the clinic uses authentic products and that the procedure is performed by a qualified professional. High-quality treatment ensures better results and safety.
To receive an accurate cost estimate, we recommend contacting Lygos Clinic directly for a personalized consultation.

Get in Touch
Get professional treatments in Turkey at Lygos Clinic, offering effective, affordable treatments for a healthier and more aesthetically pleasing life.
You can contact us via WhatsApp and Instagram for a quick response.
Frequently Asked Questions About Nucleofill
Nucleofill is done according to the needs of the patient. Therefore, effective results occur even after a single session. Generally, nucleofill is performed in 3 sessions in patients with mature skin structure.
Those who have Nucleofill DNA glow are mostly satisfied with the change experienced. Especially the rejuvenation of the skin and the reduction of signs of aging also affect many people psychologically.
The effect of nucleofill eyes lasting approximately 10 to 12 months may vary from person to person.
Nucleofill (DNA radiance) creates a natural effect on the skin. This method, which restores the vitality and moisture of the skin thanks to its beneficial ingredients, also makes patients look younger.
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